top of page
​Publications

2023

A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity

M Okamoto, M Sasai, A Kuratani, D Okuzaki, M Arai, JB. Wing, S Sakaguchi, M Yamamoto

Science Direct 42 (7), 112813

COVID-19 relapse associated with SARS-CoV-2 evasion from CD4+ T-cell recognition in an agammaglobulinemia patient

R Morita, R Kubota-Koketsu, X Lu, T Sasaki, EE Nakayama, Y Liu, ...

Iscience 26 (5)

Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19  severity

R Edahiro, Y Shirai, Y Takeshima, S Sakakibara, Y Yamaguchi, ...

Nature genetics, 1-15

Mature dendritic cells enriched in regulatory molecules may control regulatory T cells and the prognosis of head and neck cancer

K Minohara, M Imai, T Matoba, JB Wing, H Shime, M Odanaka, R Uraki, ...

Cancer Science 114 (4), 1256

Celastrol suppresses humoral immune responses and autoimmunity by targeting the COMMD3/8 complex

T Shirai, A Nakai, E Ando, J Fujimoto, S Leach, T Arimori, D Higo, ...

Science Immunology 8 (81), eadc9324

A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients

JN Søndergaard, J Tulyeu, R Edahiro, Y Shirai, Y Yamaguchi, ...

Proceedings of the National Academy of Sciences 120 (4), e2217902120

Identification of a unique subset of tissue-resident memory CD4+ T cells in Crohn’s disease

T Yokoi, M Murakami, T Kihara, S Seno, M Arase, JB Wing, ...

Proceedings of the National Academy of Sciences 120 (1), e2204269120

2022

Consecutive BNT162b2 mRNA vaccination induces short-term epigenetic memory in innate immune cells

Y Yamaguchi, Y Kato, R Edahiro, JN Søndergaard, T Murakami, S Amiya, ...

JCI insight 7 (22)

LINEAGE SWITCH IN KMT2A REARRANGED LEUKEMIA DURING BLINATUMOMAB THERAPY ACCOMPANIED BY IMMUNOLOGICAL CHANGE ANALOGOUS TO MDSC

T Mikami, I Kato, J Wing, K Tasaka, T Kamitori, H Kubota, H Hiramatsu, ...

PEDIATRIC BLOOD & CANCER 69

Regulatory T lymphocytes in cancer immunity

D Adeegbe, J Barbi, J Wing

Frontiers in Immunology 13, 1065570

Using Mass Cytometry to Address Tfh and Tfr Heterogeneity

JB Wing, S Sakaguchi

T-Follicular Helper Cells: Methods and Protocols, 47-57

DOCK2 is involved in the host genetics and biology of severe COVID-19

H Namkoong, R Edahiro, T Takano, H Nishihara, Y Shirai, K Sonehara, ...

Nature 609 (7928), 754-760

Symbiotic bacteria-dependent expansion of MR1-reactive T cells causes autoimmunity in the absence of Bcl11b

K Shibata, C Motozono, M Nagae, T Shimizu, E Ishikawa, D Motooka, ...

Nature communications 13 (1), 6948

Alteration of the immune environment in bone marrow from children with recurrent B cell precursor acute lymphoblastic leukemia

T Mikami, I Kato, JB Wing, H Ueno, K Tasaka, K Tanaka, H Kubota, ...

Cancer Science 113 (1), 41-52

2021

B cell–intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice

MSJ Lee, T Inoue, W Ise, J Matsuo-Dapaah, JB Wing, B Temizoz, ...

Journal of Experimental Medicine 219 (2), e20211336

Isolation and Characterization of Both Human and Mouse Tfh/Tfr Cells

J Tulyeu, JN Søndergaard, S Sakaguchi, JB Wing

Current Protocols 1 (11), e283

Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells

EP Mimitou, CA Lareau, KY Chen, AL Zorzetto-Fernandes, Y Hao, ...

Nature biotechnology 39 (10), 1246-1258

Arid5a promotes immune evasion by augmenting tryptophan metabolism and chemokine expression

G Parajuli, M Tekguc, JB Wing, A Hashimoto, D Okuzaki, T Hirata, ...

Cancer immunology research 9 (8), 862-876

Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells

M Tekguc, JB Wing, M Osaki, J Long, S Sakaguchi

Proceedings of the National Academy of Sciences 118 (30), e2023739118

CTLA-4 expression by B-1a B cells is essential for immune tolerance

Y Yang, X Li, Z Ma, C Wang, Q Yang, M Byrne-Steele, R Hong, Q Min, ...

Nature Communications 12 (1), 525

2020

Dynamics of effector and naïve Regulatory T cells throughout pregnancy

N Shigeta, K Kumasawa, A Tanaka, JB Wing, H Nakamura, S Sakaguchi, ...

Journal of Reproductive Immunology 140, 103135

Control of foreign Ag‐specific Ab responses by Treg and Tfr

JB Wing, EL Lim, S Sakaguchi

Immunological reviews 296 (1), 104-119

Regulatory T cells and human disease

S Sakaguchi, N Mikami, JB Wing, A Tanaka, K Ichiyama, N Ohkura

Annual review of immunology 38, 541-566

2019

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch, A Acs, D Adam, S Adam‐Klages, ...

European journal of immunology 49 (10), 1457-1973

Human FOXP3+ regulatory T cell heterogeneity and function in autoimmunity and cancer

JB Wing, A Tanaka, S Sakaguchi

Immunity 50 (2), 302-316

Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody

D Ha, A Tanaka, T Kibayashi, A Tanemura, D Sugiyama, JB Wing, EL Lim, ...

Proceedings of the National Academy of Sciences 116 (2), 609-618

Control of regulatory T cells by co-signal molecules

JB Wing, C Tay, S Sakaguchi

Co-signal Molecules in T Cell Activation: Immune Regulation in Health and …

Regulatory immune cells

JB Wing, S Sakaguchi

Clinical Immunology, 261-271. e1

© 2035 by Site Name. Powered and secured by Wix

bottom of page